SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells

SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells

<p>Abstract</p> <p>Background</p> <p>FLT3-ITD and FLT3-TKD mutations are frequently found in acute myeloid leukemia (AML). This makes tyrosine kinase FLT3 a highly attractive target for therapeutic drug development. However, effective drugs have not yet emerged. This st...

Full description

Bibliographic Details
Main Authors: Guo Yao, Chen Yun, Xu Xuesong, Fu Xueqi, Zhao Zhizhuang
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Hematology & Oncology
Subjects:
Tyrosine kinase
FLT3
Inhibitor screening
SU11652
Acute myeloid leukemia
Online Access:http://www.jhoonline.org/content/5/1/72

Internet

http://www.jhoonline.org/content/5/1/72

Similar Items