HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.

HIV controller CD4+ T cells respond to minimal amounts of Gag antigen due to high TCR avidity.

HIV controllers are rare individuals who spontaneously control HIV replication in the absence of antiretroviral treatment. Emerging evidence indicates that HIV control is mediated through very active cellular immune responses, though how such responses can persist over time without immune exhaustion...

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Bibliographic Details
Main Authors: Benoît Vingert, Santiago Perez-Patrigeon, Patricia Jeannin, Olivier Lambotte, Faroudy Boufassa, Fabrice Lemaître, William W Kwok, Ioannis Theodorou, Jean-François Delfraissy, Jacques Thèze, Lisa A Chakrabarti, ANRS EP36 HIV Controllers Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195518/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20195518/?tool=EBI

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