TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells

Multiple sclerosis (MS) is a neuroimmune disorder characterized by inflammation, CNS demyelination, and progressive neurodegeneration. Chronic MS patients exhibit impaired remyelination capacity, partly due to the changes that oligodendrocyte precursor cells (OPCs) undergo in response to the MS lesi...

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Bibliographic Details
Main Authors: Haritha L. Desu, Placido Illiano, James S. Choi, Maureen C. Ascona, Han Gao, Jae K. Lee, Roberta Brambilla
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
TNF
Online Access:https://www.mdpi.com/2073-4409/10/7/1785