TREM2 ectodomain and its soluble form in Alzheimer’s disease

Abstract Triggering receptor expressed on myeloid cells 2 (TREM2) is a receptor mainly expressed on the surface of microglia. It mediates multiple pathophysiological processes in various diseases. Recently, TREM2 has been found to play a role in the development of Alzheimer’s disease (AD). TREM2 is...

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Bibliographic Details
Main Authors: Jiaolong Yang, Zhihui Fu, Xingyu Zhang, Min Xiong, Lanxia Meng, Zhentao Zhang
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12974-020-01878-2