Pathway thermodynamics highlights kinetic obstacles in central metabolism.
In metabolism research, thermodynamics is usually used to determine the directionality of a reaction or the feasibility of a pathway. However, the relationship between thermodynamic potentials and fluxes is not limited to questions of directionality: thermodynamics also affects the kinetics of react...
Main Authors: | Elad Noor, Arren Bar-Even, Avi Flamholz, Ed Reznik, Wolfram Liebermeister, Ron Milo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-02-01
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Series: | PLoS Computational Biology |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586134/?tool=EBI |
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