Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells.

Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells.

The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown. In a placebo-controlled experimental animal study we have used multicolour fl...

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Bibliographic Details
Main Authors: Holger Hackstein, Nicole Hagel, Angela Knoche, Sabine Kranz, Jürgen Lohmeyer, Werner von Wulffen, Olivia Kershaw, Achim D Gruber, Gregor Bein, Nelli Baal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425551?pdf=render

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http://europepmc.org/articles/PMC3425551?pdf=render

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