Skin TLR7 triggering promotes accumulation of respiratory dendritic cells and natural killer cells.

The TLR7 agonist imiquimod has been used successfully as adjuvant for skin treatment of virus-associated warts and basal cell carcinoma. The effects of skin TLR7 triggering on respiratory leukocyte populations are unknown. In a placebo-controlled experimental animal study we have used multicolour fl...

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Bibliographic Details
Main Authors: Holger Hackstein, Nicole Hagel, Angela Knoche, Sabine Kranz, Jürgen Lohmeyer, Werner von Wulffen, Olivia Kershaw, Achim D Gruber, Gregor Bein, Nelli Baal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425551?pdf=render