NormQ: RNASeq normalization based on RT-qPCR derived size factors
The merit of RNASeq data relies heavily on correct normalization. However, most methods assume that the majority of transcripts show no differential expression between conditions. This assumption may not always be correct, especially when one condition results in overexpression. We present a new met...
Main Authors: | Ravindra Naraine, Pavel Abaffy, Monika Sidova, Silvie Tomankova, Kseniia Pocherniaieva, Ondrej Smolik, Mikael Kubista, Martin Psenicka, Radek Sindelka |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
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Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037020302737 |
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