New Radioligands for Describing the Molecular Pharmacology of MT1 and MT2 Melatonin Receptors

New Radioligands for Describing the Molecular Pharmacology of MT1 and MT2 Melatonin Receptors

Melatonin receptors have been studied for several decades. The low expression of the receptors in tissues led the scientific community to find a substitute for the natural hormone melatonin, the agonist 2-[125I]-iodomelatonin. Using the agonist, several hundreds of studies were conducted, including...

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Bibliographic Details
Main Authors: Olivier Nosjean, Jean A. Boutin, Jean-Louis Brayer, Philippe Delagrange, Daniel-Henri Caignard, Gérald Guillaumet, Pascal Berthelot, François Lefoulon, Emmanuel Thomas, Franck Suzenet, Benoît Folleas, Saïd Yous, Werner Hassler, Teresa Grelak, Sandrine Pedragona-Moreau, Ulrich Matthey, Céline Legros
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin receptors
2-iodomelatonin
alternative radioligands
synthesis
radiolabeling
Online Access:http://www.mdpi.com/1422-0067/14/5/8948

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http://www.mdpi.com/1422-0067/14/5/8948

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