Bone Marrow CX3CL1/Fractalkine is a New Player of the Pro-Angiogenic Microenvironment in Multiple Myeloma Patients

Bone Marrow CX3CL1/Fractalkine is a New Player of the Pro-Angiogenic Microenvironment in Multiple Myeloma Patients

C-X3-C motif chemokine ligand 1 (CX3CL1)/fractalkine is a chemokine released after cleavage by two metalloproteases, ADAM metallopeptidase domain 10 (ADAM10) and ADAM metallopeptidase domain 17 (ADAM17), involved in inflammation and angiogenesis in the cancer microenvironment. The role of the CX3CL1...

Full description

Bibliographic Details
Main Authors: Valentina Marchica, Denise Toscani, Anna Corcione, Marina Bolzoni, Paola Storti, Rosanna Vescovini, Elisa Ferretti, Benedetta Dalla Accardi, Emanuela Vicario, Fabrizio Accardi, Cristina Mancini, Eugenia Martella, Domenico Ribatti, Angelo Vacca, Vito Pistoia, Nicola Giuliani
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
multiple myeloma
angiogenesis
inflammation
CX3CL1/fractalkine
microenvironment
Online Access:http://www.mdpi.com/2072-6694/11/3/321

Internet

http://www.mdpi.com/2072-6694/11/3/321

Similar Items