Microtubule-Actomyosin Mechanical Cooperation during Contact Guidance Sensing

Summary: Cancer cell migration through and away from tumors is driven in part by migration along aligned extracellular matrix, a process known as contact guidance (CG). To concurrently study the influence of architectural and mechanical regulators of CG sensing, we developed a set of CG platforms. U...

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Bibliographic Details
Main Authors: Erdem D. Tabdanov, Vikram Puram, Alexander Zhovmer, Paolo P. Provenzano
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718314608