Propofol enhances BCR-ABL TKIs’ inhibitory effects in chronic myeloid leukemia through Akt/mTOR suppression
Abstract Background The anti-cancer activities of intravenous anesthetic drug propofol have been demonstrated in various types of cancers but not in chronic myeloid leukemia (CML). Methods We systematically examined the effect of propofol and its combination with BCR-ABL tyrosine kinase inhibitors (...
Main Authors: | Zhimin Tan, Aixia Peng, Jingwen Xu, Mingwen Ouyang |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-09-01
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Series: | BMC Anesthesiology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12871-017-0423-2 |
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