STRA6 Polymorphisms Are Associated With EGFR Mutations in Locally-Advanced and Metastatic Non-Small Cell Lung Cancer Patients

STRA6 Polymorphisms Are Associated With EGFR Mutations in Locally-Advanced and Metastatic Non-Small Cell Lung Cancer Patients

Retinol plays a significant role in several physiological processes through their nuclear receptors, whose expression depends on retinol cytoplasmic concentration. Loss of expression of nuclear receptors and low retinol levels have been correlated with lung cancer development. Stimulated by retinoic...

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Bibliographic Details
Main Authors: Saé Muñiz-Hernández, Jesús Bernardino Velázquez-Fernández, José Díaz-Chávez, Omar Mondragón-Fonseca, Yerye Mayén-Lobo, Alberto Ortega, Marisol López-López, Oscar Arrieta
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
single nucleotide polymorphisms
stimulated by retinoic acid 6 (STRA6)
genotype
retinol pathways
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.579561/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.579561/full

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