Lack of Homozygously Inactivated p73 in Single-Copy MYCN Primary Neuroblastomas and Neuroblastoma Cell Lines

Lack of Homozygously Inactivated p73 in Single-Copy MYCN Primary Neuroblastomas and Neuroblastoma Cell Lines

We examined 18 neuroblastoma cell lines and 32 primary single-copy MYCN tumor specimens to determine whether mutations of p73, a novel p53-related gene located in chromosome band 1p36.33, contribute to the genesis or progression of childhood neuroblastoma. By fluorescence in situ hybridization, 16...

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Bibliographic Details
Main Authors: Xiao-Tang Kong, Virginia A. Valentine, Susan T. Rowe, Marcus B. Valentine, Susan T. Ragsdale, Bart G. Jones, Deborah A. Wilkinson, Garrett M. Brodeur, Susan L. Cohn, A. Thomas Look
Format: Article
Language:English
Published: Elsevier 1999-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
chromosome 1p deletion
neuroblastoma
p73
tumor suppressor gene
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800384

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http://www.sciencedirect.com/science/article/pii/S1476558699800384

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