Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data.

There is increasing evidence that heritable variation in gene expression underlies genetic variation in susceptibility to disease. Therefore, a comprehensive understanding of the similarity between relatives for transcript variation is warranted--in particular, dissection of phenotypic variation int...

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Bibliographic Details
Main Authors: Joseph E Powell, Anjali K Henders, Allan F McRae, Jinhee Kim, Gibran Hemani, Nicholas G Martin, Emmanouil T Dermitzakis, Greg Gibson, Grant W Montgomery, Peter M Visscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3656157?pdf=render