Highlights on endoglin (CD105): from basic findings towards clinical applications in human cancer

<p>Abstract</p> <p>Antibody targeting of tumor-associated vasculature is a promising therapeutic approach in human cancer; however, a specific cell membrane marker for endothelial cells of tumor vasculature has not been discovered yet. Endoglin (CD105) is a cell-surface glycoprotei...

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Bibliographic Details
Main Authors: Maio Michele, Fonsatti Ester
Format: Article
Language:English
Published: BMC 2004-06-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/2/1/18