Prevalence of primary outcome changes in clinical trials registered on ClinicalTrials.gov: a cross-sectional study [v1; ref status: indexed, http://f1000r.es/34l]

Background: An important principle in the good conduct of clinical trials is that a summary of the trial protocol, with a pre-defined primary outcome, should be freely available before the study commences. The clinical trials registry ClinicalTrials.gov provides one method of doing this, and once th...

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Bibliographic Details
Main Authors: Sreeram Ramagopalan, Andrew P. Skingsley, Lahiru Handunnetthi, Michelle Klingel, Daniel Magnus, Julia Pakpoor, Ben Goldacre
Format: Article
Language:English
Published: F1000 Research Ltd 2014-03-01
Series:F1000Research
Subjects:
Online Access:http://f1000research.com/articles/3-77/v1