VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 SIGNALING AS A NOVEL MECHANISM OF T CELL SUPPRESSION IN TUMOR NEOANGIOGENESIS
The immunomodulatory activity of vascular endothelial growth factors (VEGFs) reveals a new role of neoangiogenesis in tumor development. Most of VEGF effects on T cells are mediated through the VEGF-R2 receptors. Placental growth factor (PlGF) belongs to the VEGFs family and is a selective ligand fo...
Main Authors: | , , , , |
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Format: | Article |
Language: | Russian |
Published: |
SPb RAACI
2019-10-01
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Series: | Medicinskaâ Immunologiâ |
Subjects: | |
Online Access: | https://www.mimmun.ru/mimmun/article/view/1715 |