VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 SIGNALING AS A NOVEL MECHANISM OF T CELL SUPPRESSION IN TUMOR NEOANGIOGENESIS

The immunomodulatory activity of vascular endothelial growth factors (VEGFs) reveals a new role of neoangiogenesis in tumor development. Most of VEGF effects on T cells are mediated through the VEGF-R2 receptors. Placental growth factor (PlGF) belongs to the VEGFs family and is a selective ligand fo...

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Bibliographic Details
Main Authors: E. R. Chernykh, O. Yu. Leplina, M. A. Tikhonova, E. V. Batorov, A. A. Ostanin
Format: Article
Language:Russian
Published: SPb RAACI 2019-10-01
Series:Medicinskaâ Immunologiâ
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/1715