Plasma Metabolomics Analysis of Polyvinyl Chloride Workers Identifies Altered Processes and Candidate Biomarkers for Hepatic Hemangiosarcoma and Its Development

Background: High-level occupational vinyl chloride (VC) exposures have been associated with hepatic hemangiosarcoma, which typically develops following a long latency period. Although VC is genotoxic, a more comprehensive mode of action has not been determined and diagnostic biomarkers have not been...

Full description

Bibliographic Details
Main Authors: John J. Guardiola, Josiah E. Hardesty, Juliane I. Beier, Russell A. Prough, Craig J. McClain, Matthew C. Cave
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
PVC
Online Access:https://www.mdpi.com/1422-0067/22/10/5093