Identify Down syndrome transcriptome associations using integrative analysis of microarray database and correlation-interaction network

Identify Down syndrome transcriptome associations using integrative analysis of microarray database and correlation-interaction network

Abstract Background Long non-coding RNAs (lncRNAs) have previously been emerged as key players in a series of biological processes. Dysregulation of lncRNA is correlated to human diseases including neurological disorders. Here, we developed a multi-step bioinformatics analysis to study the functions...

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Bibliographic Details
Main Authors: Min Chen, Jiayan Wang, Yingjun Luo, Kailing Huang, Xiaoshun Shi, Yanhui Liu, Jin Li, Zhengfei Lai, Shuya Xue, Haimei Gao, Allen Chen, Dunjin Chen
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Human Genomics
Subjects:
lncRNA
DSCR9
Down syndrome
Protein–protein interaction
Correlation-interaction-network
Neurological diseases
Online Access:http://link.springer.com/article/10.1186/s40246-018-0133-y

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http://link.springer.com/article/10.1186/s40246-018-0133-y

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