Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness.

Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness.

Adaptive immunity relies on the generation and maintenance of memory T cells to provide protection against repeated antigen exposure. It has been hypothesised that a self-renewing population of T cells, named stem cell-like memory T (TSCM) cells, are responsible for maintaining memory. However, it i...

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Bibliographic Details
Main Authors: Pedro Costa Del Amo, Julio Lahoz-Beneytez, Lies Boelen, Raya Ahmed, Kelly L Miners, Yan Zhang, Laureline Roger, Rhiannon E Jones, Silvia A Fuertes Marraco, Daniel E Speiser, Duncan M Baird, David A Price, Kristin Ladell, Derek Macallan, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC6033534?pdf=render

Internet

http://europepmc.org/articles/PMC6033534?pdf=render

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