Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption

Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption

<p>Abstract</p> <p>Background</p> <p>Gelsolin, an actin capping protein of osteoclast podosomes, has a unique function in regulating assembly and disassembly of the podosome actin filament. Previously, we have reported that osteopontin (OPN) binding to integrin α<sub...

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Bibliographic Details
Main Authors: Hruska Keith A, Baker De Anna, Biswas Rajat S, Chellaiah Meenakshi A
Format: Article
Language:English
Published: BMC 2004-05-01
Series:BMC Cell Biology
Subjects:
osteoclasts
actin ring
podosomes
phosphoinositides
gelsolin
WASP
Arp2/3
Online Access:http://www.biomedcentral.com/1471-2121/5/19

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http://www.biomedcentral.com/1471-2121/5/19

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