PR/SET Domain Family and Cancer: Novel Insights from the Cancer Genome Atlas

PR/SET Domain Family and Cancer: Novel Insights from the Cancer Genome Atlas

The PR/SET domain gene family (PRDM) encodes 19 different transcription factors that share a subtype of the SET domain [Su(var)3-9, enhancer-of-zeste and trithorax] known as the PRDF1-RIZ (PR) homology domain. This domain, with its potential methyltransferase activity, is followed by a variable numb...

Full description

Bibliographic Details
Main Authors: Anna Sorrentino, Antonio Federico, Monica Rienzo, Patrizia Gazzerro, Maurizio Bifulco, Alfredo Ciccodicola, Amelia Casamassimi, Ciro Abbondanza
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
PRDM gene family
TCGA data analysis
somatic mutations
transcriptome profiling
human malignancies
Online Access:http://www.mdpi.com/1422-0067/19/10/3250

Internet

http://www.mdpi.com/1422-0067/19/10/3250

Similar Items