Genome-Wide Identification and Analysis of Enhancer-Regulated microRNAs Across 31 Human Cancers

Genome-Wide Identification and Analysis of Enhancer-Regulated microRNAs Across 31 Human Cancers

Enhancers are cis-regulatory DNA elements that positively regulate the transcription of target genes in a tissue-specific manner, and dysregulation of target genes could lead to various diseases, such as cancer. Recent studies have shown that enhancers can regulate microRNAs (miRNAs) and participate...

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Bibliographic Details
Main Authors: Fei Tang, Yin Zhang, Qing-Qing Huang, Ming-Ming Qian, Zhi-Xue Li, Yan-Jing Li, Bei-Ping Li, Zheng-Liang Qiu, Jun-Jie Yue, Zhi-Yun Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
enhancer
microRNA
cancer
transcriptional regulation
TCGA
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00644/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00644/full

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