E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.

E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis.

Chronic hepatic damage leads to liver fibrosis, which is characterized by the accumulation of collagen-rich extracellular matrix. However, the mechanism by which E3 ubiquitin ligase is involved in collagen synthesis in liver fibrosis is incompletely understood. This study aimed to explore the involv...

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Bibliographic Details
Main Authors: Daisuke Hasegawa, Ryoji Fujii, Naoko Yagishita, Nobuyuki Matsumoto, Satoko Aratani, Toshihiko Izumi, Kazuko Azakami, Minako Nakazawa, Hidetoshi Fujita, Tomoo Sato, Natsumi Araya, Junki Koike, Mamoru Tadokoro, Noboru Suzuki, Kazuhiro Nagata, Haruki Senoo, Scott L Friedman, Kusuki Nishioka, Yoshihisa Yamano, Fumio Itoh, Toshihiro Nakajima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2963597?pdf=render

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http://europepmc.org/articles/PMC2963597?pdf=render

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