Obesity as an Early Symptom of the AMIS Syndrome

We review evidence that the AMIS (Absence of Meal-induced Insulin Sensitization) syndrome describes a paradigm fundamental to development of obesity. The hypoglycemic response to a pulse of insulin is doubled after a meal as a result of Hepatic Insulin Sensitizing Substance (HISS), released from the...

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Bibliographic Details
Main Authors: W. Wayne Lautt, Hui Helen Wang
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/3/4/1178