Fetal Haemoglobin and β-globin Gene Cluster Haplotypes among Sickle Cell Patients in Chhattisgarh

ABSTRACT Background: Foetal Haemoglobin (HbF) is the best-known genetic modulator of sickle cell anaemia, which varies dramatically in concentration in the blood of these patients. The patients with SCA display a remarkable variability in the disease severity. High HbF levels and the β-globin g...

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Bibliographic Details
Main Authors: Sanjana Bhagat, Pradeep Kumar Patra, Amar Singh Thakur
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2013-02-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/2744/20-%204381_PF1(M)_E(C)_F(T)_PF1(T)_FA(T).pdf