Rapid Detection of HLA-B*57:01-Expressing Cells Using a Label-Free Interdigitated Electrode Biosensor Platform for Prevention of Abacavir Hypersensitivity in HIV Treatment

Rapid Detection of HLA-B*57:01-Expressing Cells Using a Label-Free Interdigitated Electrode Biosensor Platform for Prevention of Abacavir Hypersensitivity in HIV Treatment

Pre-treatment screening of individuals for human leukocyte antigens (HLA) HLA-B*57:01 is recommended for the prevention of life-threatening hypersensitivity reactions to abacavir, a drug widely prescribed for HIV treatment. However, the implementation of screening in clinical practice is hindered by...

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Bibliographic Details
Main Authors: Jianxiong Chan, Gita V. Soraya, Lauren Craig, Shah M. Uddin, Marian Todaro, Duc H. Huynh, Chathurika D. Abeyrathne, Lyudmila Kostenko, James McCluskey, Efstratios Skafidas, Patrick Kwan
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Sensors
Subjects:
human leukocyte antigen
interdigitated electrodes
impedance sensor
protein sensor
point-of-care diagnostics
pharmacogenetics
Online Access:https://www.mdpi.com/1424-8220/19/16/3543

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https://www.mdpi.com/1424-8220/19/16/3543

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