Evaluating The Role Of Nitric Oxide Synthase In Oncogenic Ras-Driven Tumorigenesis
We previously reported that oncogenic KRAS activation of the PI3K/AKT pathway stimulates the remaining wild-type HRAS and NRAS proteins in a manner dependent upon both eNOS expression and C118 in HRAS and NRAS, which promoted tumor growth. Interestingly however, we recently found that loss of wild-t...
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| Format: | Article |
| Language: | English |
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Elsevier
2015-08-01
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| Series: | Redox Biology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213231715001342 |