Mitochondrial Perturbation Contributing to Cognitive Decline in Streptozotocin-Induced Type 1 Diabetic Rats

Mitochondrial Perturbation Contributing to Cognitive Decline in Streptozotocin-Induced Type 1 Diabetic Rats

Background/Aims: Mitochondrial perturbation is a well-established cause of cognitive decline, but as yet it is unclear how mitochondria-associated neuronal abnormalities in type 1 diabetic (T1DM) brain contribute to cognitive decline. Methods: The streptozotocin (STZ)-induced mouse model of T1DM was...

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Bibliographic Details
Main Authors: Yu Zhou, Siheng Lian, Jin Zhang, Donghai Lin, Caihua Huang, Libin Liu, Zhou Chen
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Type 1 diabetes
Diabetic encephalopathy
Mitochondrial perturbation
Mitochondrial dynamics
Metabolomic analysis
Online Access:https://www.karger.com/Article/FullText/489243

Internet

https://www.karger.com/Article/FullText/489243

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