Apicobasal polarity and its role in cancer progression

Appropriate establishment and maintenance of cell polarity is essential for normal development and homeostasis. The vast majority of human cancers originate from epithelial tissues and tumour cell invasion and metastasis are the major cause of mortality in human cancers. Invading cells demonstrate l...

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Bibliographic Details
Main Authors: Lo Priscilla, Hawrot Hannah, Georgiou Marios
Format: Article
Language:English
Published: De Gruyter 2012-12-01
Series:Biomolecular Concepts
Subjects:
Online Access:https://doi.org/10.1515/bmc-2012-0020