Cerebral hemispheric glioblastoma with PNET-like morphology and histone H3.3 G34 mutation in younger patients: Report of three rare cases and diagnostic pitfalls

Cerebral hemispheric glioblastoma with PNET-like morphology and histone H3.3 G34 mutation in younger patients: Report of three rare cases and diagnostic pitfalls

Recurrent mutations in H3F3A that encodes the histone 3 variant H3.3, lead to amino acid substitutions including K27M and G34R/V-which are observed in high-grade gliomas (HGGs) of children and young adults. Previous studies have focused on gliomas with K27M mutation, whereas gliomas with G34R/V muta...

Full description

Bibliographic Details
Main Authors: Yuanyuan Cheng, Weiqi Bao, Qian Wu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
cerebral hemisphere
glioblastoma
h3.3 g34 mutation
h3f3a
pnet-like
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2020;volume=63;issue=2;spage=262;epage=266;aulast=Cheng

Internet

http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2020;volume=63;issue=2;spage=262;epage=266;aulast=Cheng

Similar Items