Ex Vivo Major Histocompatibility Complex I Knockdown Prolongs Rejection-free Allograft Survival

Background:. Widespread application of vascularized composite allotransplantation (VCA) is currently limited by the required lifelong systemic immunosuppression and its associated morbidity and mortality. This study evaluated the efficacy of ex vivo (after procurement but before transplantation) eng...

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Bibliographic Details
Main Authors: Jessica B. Chang, MD, William J. Rifkin, BA, Marc A. Soares, MD, April Duckworth, MD, Nakul Rao, MD, Yee Cheng Low, MD, Jonathan P. Massie, MD, Piul S. Rabbani, PhD, Pierre B. Saadeh, MD, Daniel J. Ceradini, MD
Format: Article
Language:English
Published: Wolters Kluwer 2018-06-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000001825