The Molecular Basis of Human Anophthalmia and Microphthalmia

Human eye development is coordinated through an extensive network of genetic signalling pathways. Disruption of key regulatory genes in the early stages of eye development can result in aborted eye formation, resulting in an absent eye (anophthalmia) or a small underdeveloped eye (microphthalmia) ph...

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Bibliographic Details
Main Authors: Philippa Harding, Mariya Moosajee
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Journal of Developmental Biology
Subjects:
eye
Online Access:https://www.mdpi.com/2221-3759/7/3/16