Caveolin-1 scaffolding domain peptide regulates glucose metabolism in lung fibrosis

Increased metabolism distinguishes myofibroblasts or fibrotic lung fibroblasts (fLfs) from the normal lung fibroblasts (nLfs). The mechanism of metabolic activation in fLfs has not been fully elucidated. Furthermore, the antifibrogenic effects of caveolin-1 scaffolding domain peptide CSP/CSP7 involv...

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Bibliographic Details
Main Authors: Venkadesaperumal Gopu, Liang Fan, Rashmi S. Shetty, M.R. Nagaraja, Sreerama Shetty
Format: Article
Language:English
Published: American Society for Clinical investigation 2020-10-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.137969