Activating a Reserve Neural Stem Cell Population In Vitro Enables Engraftment and Multipotency after Transplantation

Summary: The olfactory epithelium (OE) regenerates after injury via two types of tissue stem cells: active globose cells (GBCs) and dormant horizontal basal cells (HBCs). HBCs are roused to activated status by OE injury when P63 levels fall. However, an in-depth understanding of activation requires...

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Bibliographic Details
Main Authors: Jesse Peterson, Brian Lin, Camila M. Barrios-Camacho, Daniel B. Herrick, Eric H. Holbrook, Woochan Jang, Julie H. Coleman, James E. Schwob
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671119300852