Efficient Genome-wide Association in Biobanks Using Topic Modeling Identifies Multiple Novel Disease Loci
Abstract Biobanks and national registries represent a powerful tool for genomic discovery, but rely on diagnostic codes that can be unreliable and fail to capture relationships between related diagnoses. We developed an efficient means of conducting genome-wide association studies using combinations...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-08-01
|
| Series: | Molecular Medicine |
| Online Access: | http://link.springer.com/article/10.2119/molmed.2017.00100 |