Retrograde Synaptic Signaling Mediated by K+ Efflux through Postsynaptic NMDA Receptors

Retrograde Synaptic Signaling Mediated by K+ Efflux through Postsynaptic NMDA Receptors

Synaptic NMDA receptors (NMDARs) carry inward Ca2+ current responsible for postsynaptic signaling and plasticity in dendritic spines. Whether the concurrent K+ efflux through the same receptors into the synaptic cleft has a physiological role is not known. Here, we report that NMDAR-dependent K+ ef...

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Bibliographic Details
Main Authors: Pei-Yu Shih, Leonid P. Savtchenko, Naomi Kamasawa, Yulia Dembitskaya, Thomas J. McHugh, Dmitri A. Rusakov, Ryuichi Shigemoto, Alexey Semyanov
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713006104

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http://www.sciencedirect.com/science/article/pii/S2211124713006104

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