RelB regulates the homeostatic proliferation but not the function of Tregs

RelB regulates the homeostatic proliferation but not the function of Tregs

Abstract Background RelB, a member of the NF-κB family, plays a critical role in the development of T cells. However, the role of RelB in Foxp3+ regulatory T cells (Tregs) remains controversial. Results Using a bone marrow chimeric mouse model, we demonstrated that the expansion of Foxp3+ Tregs in v...

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Bibliographic Details
Main Authors: Shuping Zhou, Weiwei Wu, Zhaoxia Wang, Zhaopeng Wang, Qinghong Su, Xiaofan Li, Yong Yu, Weidong Zhang, Mingzhao Zhu, Wei Lin
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Immunology
Subjects:
RelB
Treg
Cells proliferation
STAT5
Online Access:http://link.springer.com/article/10.1186/s12865-020-00366-9

Internet

http://link.springer.com/article/10.1186/s12865-020-00366-9

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