The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats.

Erectile dysfunction (ED) is a common clinical disease that is difficult to treat. We previously found that hypoxia modulates the phenotype of primary corpus cavernosum smooth muscle cells (CCSMCs) in rats, but the underlying molecular mechanism is still unknown. Platelet-derived growth factor recep...

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Bibliographic Details
Main Authors: Jun-Feng Yan, Wen-Jie Huang, Jian-Feng Zhao, Hui-Ying Fu, Gao-Yue Zhang, Xiao-Jun Huang, Bo-Dong Lv
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5330473?pdf=render