Polymorphic sites at the 3' untranslated region of the HLA-G gene are associated with differential hla-g soluble levels in the Brazilian and French population.

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows lower frequency of polymorphism at the coding region but higher variability at regulatory 5' and 3' untranslated (3'UTR) regions. At least three 3'UTR polymorphic sites have been associated wit...

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Bibliographic Details
Main Authors: Gustavo Martelli-Palomino, Joao A Pancotto, Yara C Muniz, Celso T Mendes-Junior, Erick C Castelli, Juliana D Massaro, Irene Krawice-Radanne, Isabelle Poras, Vera Rebmann, Edgardo D Carosella, Nathalie Rouas-Freiss, Philippe Moreau, Eduardo A Donadi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3808361?pdf=render