In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example

In Vivo Expansion of Cancer Stemness Affords Novel Cancer Stem Cell Targets: Malignant Rhabdoid Tumor as an Example

Summary: Cancer stem cell (CSC) identification relies on transplantation assays of cell subpopulations sorted from fresh tumor samples. Here, we attempt to bypass limitations of abundant tumor source and predetermined immune selection by in vivo propagating patient-derived xenografts (PDX) from huma...

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Bibliographic Details
Main Authors: Hana Golan, Rachel Shukrun, Revital Caspi, Einav Vax, Naomi Pode-Shakked, Sanja Goldberg, Oren Pleniceanu, Dekel D. Bar-Lev, Michal Mark-Danieli, Sara Pri-Chen, Jasmine Jacob-Hirsch, Itamar Kanter, Ariel Trink, Ginette Schiby, Ron Bilik, Tomer Kalisky, Orit Harari-Steinberg, Amos Toren, Benjamin Dekel
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118303151

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http://www.sciencedirect.com/science/article/pii/S2213671118303151

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