Novel Activity Detection Algorithm to Characterize Spontaneous Stepping During Multimodal Spinal Neuromodulation After Mid-Thoracic Spinal Cord Injury in Rats

Novel Activity Detection Algorithm to Characterize Spontaneous Stepping During Multimodal Spinal Neuromodulation After Mid-Thoracic Spinal Cord Injury in Rats

A mid-thoracic spinal cord injury (SCI) severely impairs activation of the lower limb sensorimotor spinal networks, leading to paralysis. Various neuromodulatory techniques including electrical and pharmacological activation of the spinal networks have been successful in restoring locomotor function...

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Bibliographic Details
Main Authors: Raymond Chia, Hui Zhong, Bryce Vissel, V. Reggie Edgerton, Parag Gad
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Systems Neuroscience
Subjects:
sub-threshold spinal cord stimulation
spinal cord injury
spontaneous cage activity
EMG
muscle coordination
strychnine
Online Access:https://www.frontiersin.org/article/10.3389/fnsys.2019.00082/full

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https://www.frontiersin.org/article/10.3389/fnsys.2019.00082/full

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