NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female

NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female

Nucleotides released by smooth muscle cells (SMCs) and by innervating nerve terminals activate specific P2 receptors and modulate bladder contraction. We hypothesized that cell surface enzymes regulate SMC contraction in mice bladder by controlling the concentration of nucleotides. We showed by immu...

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Bibliographic Details
Main Authors: Romuald Brice Babou Kammoe, Gilles Kauffenstein, Julie Pelletier, Bernard Robaye, Jean Sévigny
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Biomolecules
Subjects:
NTPDase1
extracellular nucleotides
bladder
smooth muscle cells
contraction
P2Y<sub>6</sub> receptor
Online Access:https://www.mdpi.com/2218-273X/11/2/147

Internet

https://www.mdpi.com/2218-273X/11/2/147

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