Genome-wide target profiling of <it>piggyBac </it>and <it>Tol2 </it>in HEK 293: pros and cons for gene discovery and gene therapy

<p>Abstract</p> <p>Background</p> <p>DNA transposons have emerged as indispensible tools for manipulating vertebrate genomes with applications ranging from insertional mutagenesis and transgenesis to gene therapy. To fully explore the potential of two highly active DNA...

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Bibliographic Details
Main Authors: Yu Robert K, Chung Pei-Cheng, Yang Herng-Shing, Weirauch Matthew T, Meir Yaa-Jyuhn J, Wu Sareina C-Y
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/11/28