Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans

Okabe et al. show that the miRNA production system in the neuron and the small RNA transport machinery in the intestine are required for the acquisition of hormesis. For its inheritance, both the transport of small RNAs in the germline and the germline Argonaute HRDE-1 complex are needed, highlighti...

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Bibliographic Details
Main Authors: Emiko Okabe, Masaharu Uno, Saya Kishimoto, Eisuke Nishida
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01692-3