Comparison of deuterium incorporation and mass isotopomer distribution analysis for measurement of human cholesterol biosynthesis

Comparison of deuterium incorporation and mass isotopomer distribution analysis for measurement of human cholesterol biosynthesis

To compare endogenous cholesterol biosynthesis measured by deuterium incorporation (DI) and mass isotopomer distribution analysis (MIDA), cholesterol fractional and absolute synthetic rates were measured simultaneously by both techniques under identical physiological conditions. Twelve subjects (22...

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Bibliographic Details
Main Authors: Marco Di Buono, Peter J.H. Jones, Louis Beaumier, Linda J. Wykes
Format: Article
Language:English
Published: Elsevier 2000-09-01
Series:Journal of Lipid Research
Subjects:
deuterium incorporation
mass isotopomer distribution analysis
cholesterol biosynthesis
stable isotopes
mass spectrometry
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520334647

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http://www.sciencedirect.com/science/article/pii/S0022227520334647

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