Efficacy, safety, and tolerability of combined pirfenidone and N-acetylcysteine therapy: a systematic review and meta-analysis

Efficacy, safety, and tolerability of combined pirfenidone and N-acetylcysteine therapy: a systematic review and meta-analysis

Abstract Background While antifibrotic drugs significantly decrease lung function decline in idiopathic pulmonary fibrosis (IPF), there is still an unmet need to halt disease progression. Antioxidative therapy with N-acetylcysteine (NAC) is considered a potential additional therapy that can be combi...

Full description

Bibliographic Details
Main Authors: Hanyu Shi, Dawei Yin, Francesco Bonella, Michael Kreuter, Ute Oltmanns, Xuren Li, Shouchun Peng, Luqing Wei
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Pulmonary Medicine
Subjects:
Idiopathic pulmonary fibrosis
Pirfenidone
Acetylcysteine
Meta-analysis
Systematic review
Online Access:http://link.springer.com/article/10.1186/s12890-020-1121-2

Internet

http://link.springer.com/article/10.1186/s12890-020-1121-2

Similar Items