Implication of human UGT2B7, 2B15 and 2B17 in 19-norandrosterone metabolism

Implication of human UGT2B7, 2B15 and 2B17 in 19-norandrosterone metabolism

Nandrolone (19-nortestosterone) is an anabolic androgenic steroid commonly abused for doping purposes. Nandrolone is mainly metabolized in the liver into 19-norandrosterone prior to glucuronidation and excretion through urine over an extended period of time. Several UGTs (i.e. UGT2B7, UGT2B15 and UG...

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Bibliographic Details
Main Authors: Emmanuel eStrahm, Ulf eSjöberg, Mats eGarle, Anders eRane, Lena eEkström
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Endocrinology
Subjects:
Nandrolone
anabolic androgenic steroid
19-norandrosterone
UGT2B7
UGT2B15
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00075/full

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http://journal.frontiersin.org/Journal/10.3389/fendo.2013.00075/full

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