Anthocyanin-rich mulberry fruit improves insulin resistance and protects hepatocytes against oxidative stress during hyperglycemia by regulating AMPK/ACC/mTOR pathway

This study evaluated the capacity of mulberry anthocyanin extract (MAE) on oxidative damage alleviation and related protein expression regulation in HepG2 cells and type 2 diabetic mice. In vitro, exposure of cells to high glucose and palmitic acid resulted in ROS and O2− accumulation, mitochondria...

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Bibliographic Details
Main Authors: Fujie Yan, Xiaodong Zheng
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617300373