Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study

Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study

Abstract Background Fibrosis is an integral component of the pathogenesis of acute lung injury and is associated with poor outcomes in patients with acute respiratory distress syndrome (ARDS). Fibrocytes are bone marrow-derived cells that traffic to injured tissues and contribute to fibrosis; hence...

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Bibliographic Details
Main Authors: Christine M. Lin, Abdullah Alrbiaan, John Odackal, Zhimin Zhang, Yogesh Scindia, Sun-Sang J. Sung, Marie D. Burdick, Borna Mehrad
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Molecular Medicine
Subjects:
Acute lung injury
Respiratory distress syndrome (adult)
Pneumonia
Fibrosis
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s10020-020-00176-0

Internet

http://link.springer.com/article/10.1186/s10020-020-00176-0

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